池毓烺(1982.11),博士、副教授、硕士生导师、九三学社社员。主要从事环境微生物、环境微生态与健康方面的工作,重点关注环境(肠道)微生物与健康的关系。先后主持和参加各级科研项目10多项,其中主持国家自然科学基金项目1项、福建省自然科学基金面上项目1项、中国科学院重点实验室项目2项。目前已在国内外学术期刊发表科研论文27篇,其中第一及通讯作者SCI论文10篇。
论文
1. Chi, Y., Lin, Y., Lu, Y., Huang, Q., Ye, G., & Dong, S. (2019). Gut microbiota dysbiosis correlates with a low-dose PCB126-induced dyslipidemia and non-alcoholic fatty liver disease.Science of the Total Environment, 653, 274-282.
2. Chi, Y., Lin, Y., Zhu, H., Huang, Q., Ye, G., & Dong, S. (2018). PCBs-high-fat diet interactions as mediators of gut microbiotadysbiosis and abdominal fat accumulation in female mice. Environmental Pollution, 239, 332-341.
3. Chi, Y., Wang, H., Lin, Y., Lu, Y., Huang, Q., Ye, G., & Dong, S. (2019). Gut microbiota characterization and lipid metabolism disorder found in PCB77-treated female mice. Toxicology, 420, 11-20.
4. Chi, Y., Zhang, H., Huang, Q., Lin, Y., Ye, G., Zhu, H., & Dong, S. (2018). Environmental risk assessment of selected organic chemicals based on TOC test and QSAR estimation models. Journal of Environmental Sciences,64, 23-31.
5. Chi, Y., Huang, Q., Lin, Y., Ye, G., Zhu, H., & Dong, S. (2018). Epithelial-mesenchymal transition effect of fine particulate matter from the Yangtze River Delta region in China on human bronchial epithelial cells. Journal of Environmental Sciences, 66, 155-164.
6. Chi, Y., Wu, Z., Zhong, Y., & Dong, S. (2017). Enantiomeric resolution, stereochemical assignment and toxicity evaluation of TPA enantiomers. Biomedical Chromatography, 31(8), e3924.
7. Chi, Y., Huang, Q., Zhang, H., Chen, Y., & Dong, S. (2016). In situ combined chemical and biological assessment of estrogenic pollution in a water recycling system. Journal of Environmental Sciences, 43, 216-223.
8. Chi, Y. L., Zhang, H. Y., Xue, J. H., Hao, J., Liu, M. F., & Wei, X. Y. (2009). N 2-(1-Methoxycarbonylethyl) guanosine, a new nucleoside coupled with an amino acid derivative from Amanita exitialis. Chinese Chemical Letters, 20 (7), 830-832.
9. Chi, Y. L., Min L. L., Dong, S. J. (2015). Chemical Constituents from Amanita Exitialis. Natural product research and development, 27 (Suppl) 21-23. (In Chinese).
10. Wang, H., Zhu, Y., Chi, Y., & Dong, S. (2019). A human embryonic stem cell-based model for benzo[a]pyrene-induced embryotoxicity. Reproductive Toxicology, 85, 26-33. (通讯作者)
11. Wang, H., Zhao, P., Huang, Q., Chi, Y., Dong, S., Fan, J. (2019). Bisphenol-A induces neurodegeneration through disturbance of intracellular calcium homeostasis in human embryonic stem cells-derived cortical neurons. Chemosphere, 229, 618-630. (通讯作者)
12. Gao, H., Ye, G., Lin, Y., Chi, Y., & Dong, S. (2020). Benzo [a] pyrene at human blood equivalent level induces human lung epithelial cell invasion and migration via aryl hydrocarbon receptor signaling. Journal of Applied Toxicology.
13. Ye, G., Ding, D., Gao, H., Chi, Y., Chen, J., Wu, Z., ...& Dong, S. (2019). Comprehensive metabolic responses of HepG2 cells to fine particulate matter exposure: Insights from an untargeted metabolomics. Science of The Total Environment, 691, 874-884.
14. Ye, G., Chen, G., Gao, H., Lin, Y., Liao, X., Zhang, H., Liu, X., Chi, Y., Huang, Q., Zhu, H., Fan, Y., Dong, S. (2019). Resveratrol inhibits lipid accumulation in the intestine of atherosclerotic mice and macrophages. Journal of Cellular and Molecular Medicine, 1-13.
15. Ye, G., Gao, H., Lin, Y., Ding, D., Liao, X., Zhang, H., Chi, Y., & Dong, S. (2019). Peroxisome proliferator-activated receptor A/G reprogrammes metabolism associated with lipid accumulation in macrophages. Metabolomics, 15(3), 36.
16. Ding, D., Ye, G., Lin, Y., Lu, Y., Zhang, H., Zhang, X., Hong, Z., Huang, Q., Chi, Y.,...& Dong, S. (2019). MicroRNA-26a-CD36 signaling pathway: Pivotal role in lipid accumulation in hepatocytes induced by PM2. 5 liposoluble extracts. Environmental Pollution, 248, 269-278.
17. Ye, G., Gao, H., Wang, Z., Lin, Y., Liao, X., Zhang, H.,Chi, Y., Zhu, H., Dong, S. (2019). PPARα and PPARγ activation attenuates total free fatty acid and triglyceride accumulation in macrophages via the inhibition of Fatp1 expression. Cell Death & Disease, 10(2), 39-39.
18. Huang, Q., Liu, Y., Chen, Y., Fang, C., Chi, Y., Zhu, H., ...& Dong, S. (2018). New insights into the metabolism and toxicity of bisphenolA on marine fish under long-term exposure. Environmental Pollution, 242, 914-921.
19. Huang, Q., Chi, Y., Deng, J., Liu, Y., Lu, Y., Chen, J., & Dong, S. (2017). Fine particulate matter 2.5 exerted its toxicological effect by regulating a new layer, long non-coding RNA. Scientific reports, 7(1), 9392.
20. Huang, Q., Chen, Y., Lin, L., Liu, Y., Chi, Y., Lin, Y., ...& Dong, S. (2017). Different effects of bisphenol A and its halogenated derivatives on the reproduction and development of Oryziasmelastigma under environmentally relevant doses. Science of the Total Environment, 595, 752-758.
21. Lu, Y. Y., Lin, Y., Ding, D. X., Su, S., Chi, Q. Q., Zhang, Y. C., ...&Chi, Y. L. (2017). MiR-26a functions as a tumor suppressor in ambient particulate matter-bound metal-triggered lung cancer cell metastasis by targeting LIN28B–IL6–STAT3 axis. Archives of toxicology, 92:1023-1035.
22. Lin, Y., Ding, D., Huang, Q., Liu, Q., Lu, H., Liu, Y., Chi, Y., ...& Wei, J. (2017). Downregulation of miR-192 Causes Hepatic Steatosis and Lipid Accumulation by Inducing SREBF1: Novel Mechanism for Bisphenol A-triggered Non-alcoholic Fatty Liver Disease. BiochimicaetBiophysicaActa (BBA)-Molecular and Cell Biology of Lipids, 1862(9), 869-882.
23. Ye, G., Chen, Y., Wang, H. O., Ye, T., Lin, Y., Huang, Q., Chi, Y., ...& Dong, S. (2016). Metabolomics approach reveals metabolic disorders and potential biomarkers associated with the developmental toxicity of tetrabromobisphenol A and tetrachlorobisphenol A. Scientific reports, 6.
24. Lu, Y. Y., Lin, Y., Zhang, H., Ding, D., Sun, X., Huang, Q., ...Chi, Y., & Dong, S. (2016). Evaluation of Volatile Organic Compounds and Carbonyl Compounds Present in the Cabins of Newly Produced, Medium-and Large-Size Coaches in China. International journal of environmental research and public health, 13(6), 596.
25. Huang, Q., Zhang, H., Chen, Y. J., Chi, Y. L., & Dong, S. (2016). The inflammation response to DEHP through PPARγ in endometrial cells. International journal of environmental research and public health, 13(3), 318.
26. Huang, Q., Chen, Y., Chi, Y., Lin, Y., Zhang, H., Fang, C., & Dong, S. (2015). Immunotoxic effects of perfluorooctanesulfonate and di (2-ethylhexyl) phthalate on the marine fish Oryziasmelastigma. Fish & shellfish immunology, 44(1), 302-306.
27. Xue, J. H., Wu, P., Chi, Y. L., Xu, L. X., & Wei, X. Y. (2011). Cyclopeptides from Amanita exitialis. Natural products and bioprospecting, 1(1), 52-56.
项目:
1. 国家自然科学基金项目,41701576,主持。
2. 中国科学院城市环境与健康重点实验室跨组合作项目,KLUEH-C-201901,主持。
3. 中国科学院城市环境与健康重点实验室跨组合作项目,KLUEH-C-201802,主持。
4. 福建省自然科学基金面上项目,2018J01022,主持。
5. 国家自然科学基金面上项目,21777158,参加。
6. 国家自然科学基金面上项目,21477124,参加。
7. 国家自然科学基金青年项目,21507128,参加。
8. 福建省中科院STS计划项目,2016T3005,参加。
9. 福建省自然科学基金项目,2017J01028,参加。
10. 福建省自然科学基金引导性项目,2018Y0081,参加。
11. 福建省自然科学基金项目,2018J01020,参加。